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People with heart problems are at increased risk of cardiovascular side effects such as heart attack, stroke, chest pain, high blood pressure and abnormal heartbeat

Histamine-2 blockers (like famotidine) or proton pump inhibitors (like omeprazole) reduce overall stomach acid production and work well if heartburn occurs regularly during your first weeks on treatment

How Retatrutide and Zepbound Work Differently in the Body The core difference in the Retatrutide vs Zepbound comparison comes down to receptor activation